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These negative effects are most pronounced in women with polycystic ovary syndrome (PCOS)

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albicans can resist them through specific signaling pathways [50, 51]

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This hypersensitivity for GH further pushes up the already elevated IGF-1 production, while on top of that IGF-1 actions are also increased because of the hyperinsulinemia-induced reduction in IGFBP-1 [35]

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