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Preclinical results are consistently positive in tissue repair contexts, but animal data cannot confirm human efficacy
F., & Tsao, G
EGR-1 and FAK Cytoskeletal Organization: Tissue biology literature suggests that BPC-157 promotes cellular migration and tissue remodeling in experimental models (Chang et al., 2014)
However, when there is an excess amount of cytosolic DA outside of the synaptic vesicle in damaged neurons, i.e., after L-DOPA treatment, DA is easily metabolized via monoamine oxidase (MAO) or by auto-oxidation to cytotoxic ROS (Zucca et al., 2014)
Most human DSIP studies are more than 30 years old and were conducted before many modern clinical-trial standards became routine
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