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A mismatch can develop between the haptocorrin-bound pool, which makes up most of the total, and the smaller active fraction on transcobalamin that cells depend on
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If You Have No Absorption Issues : If your body absorbs B12 effectively from the digestive tract, oral supplements can be a great option for maintaining adequate levels over time
This means most of a high-dose supplement remains in the gastrointestinal tract, though the direct link to digestive symptoms is not well established
1 2 "Vegan diet, subnormal vitamin B-12 status and cardiovascular health"
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