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These approaches should be implemented proactively, particularly during treatment initiation and dose escalation
The is also a range of other non-enzymatic antioxidants that take part in the defense against the reactive oxygen species in the biological systems like, for exemple, the ubiquinone, the ceruloplasmin, the uric acid, the taurine, the flavonoids and other fenolic compounds of vegetal origin (Halliwell 1990, Cutler, 1991, Sies, 1991)