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From a pharmacokinetic perspective, studies indicate no evidence that the combination of Vitamins B1, B6, and B12 adversely affects the pharmacokinetics of each individual vitamin

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This has been demonstrated using electron paramagnetic resonance (EPR) spectroscopy measurements [77] and electron spin resonance (ESR) spin-trapping studies [46] , approaches often combined with hepatic copper measurements in Wilson disease patients using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) [21]

As more data and testimonials came out on Nitrosigine, though, it became clear that Nitrosigine's NO boosting wasn't just improving athletic performance: it was having some pretty serious nootropic effects as well