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A significant decrease of at least 2 points in the histological SAF-A score (the activity component of the Steatosis, Activity, Fibrosis [SAF] scoring system that incorporates scores for ballooning and inflammation) without worsening of liver fibrosis was observed in 55% of participants treated with 1200 mg of lanifibranor compared with 33% in the placebo group
However, other countries outside of the U.S
2025, pp
Understanding the root causewhether biological, behavioral, or geneticis essential before changing your regimen
In PIONEER 4, additional anti-diabetic medication and rescue medication use was more than double in the placebo treatment group compared to the semaglutide 14 mg and LIRA 1.8 mg treatment groups
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