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the human RCTs that put it ahead of most brain-fog fads Chandrasekhar 2012 (~27.9% lower cortisol), Choudhary 2017 in the Journal of Dietary Supplements (better memory, attention and executive function), Salve 2019 and Gopukumar 2021
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Earlier GHRPs GHRP-2 and GHRP-6, the two peptides ipamorelin replaced in most compounding protocols, both trigger cortisol and, to varying degrees, prolactin release via off-target receptor binding
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Key research areas include tendon, ligament, and muscle repair BPC-157 has been studied in multiple preclinical models of connective tissue injury, with published results showing accelerated recovery timelines compared to controls
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