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Although there is a concern for the development of rare pancreatitis, pancreatic cancer or thyroid cancer, a meta-analysis of several databases did not suggest any increased risk of acute pancreatitis or pancreatic cancer with GLP-1RA treatment in T2DM patients [17]
One unanswered question is whether long-term use could lead to reduced responsiveness over time
Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
Grudzien-Nogalska et al
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