tirzepatide targets Efficacy of versus semaglutide in achieving therapeutic in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial | Diabetologia is glp 1 the same

These components work through different mechanismshelping regulate appetite, metabolism, insulin response, and energy utilization

Building sustainable eating habits during this period of reduced appetite creates structures that support weight maintenance after treatment ends or doses stabilize

However, fasting also predictably induces compensatory physiologic responses, such as increased appetite signaling and reduced energy expenditure, which may undermine long-term durability

As a GP, I find this worrying, says Dr Mahmoud Elkhouly, a regenerative medicine specialist who also runs The Ghanem Clinic s weight loss programme

Medications such as GLP-1 receptor agonists work best when used as part of a comprehensive, medically guided plan rather than as a stand-alone solution