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Dosing After Reconstitution With a 10 mg vial reconstituted in 2 mL BAC water (5 mg/mL concentration): For the 8 mg and 12 mg doses, a higher concentration is more practical
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No adverse developmental outcomes were observed in offspring when alogliptin was administered to pregnant rats during gestation and lactation at doses up to 250 mg/kg (~95 times the 25 mg clinical dose, based on AUC)
Compounding this, chronic pain limits physical activity, further reducing daily energy expenditure and creating a cycle that favors weight gain
