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i 2+ K : Beta-2 receptor stimulation has been shown to stimulate calcium-activated potassium (KCa) channels in airway smooth muscle by both PKA-induced phosphorylation, and membrane-delimited Gs pathways (Kume et al, 1994)
References Muday, G
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IGF-1 LR3 bypasses this because it doesnt bind IGFBP-3 or other binding proteins effectively
(And Why the Name Is Ambiguous) Melanotan 2 is a different molecule: a synthetic cyclic heptapeptide (7 amino acids, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH 2 )
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