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Niacinamide Niacinamide (vitamin B3) has been examined for its ability to influence the transfer of pigment-containing melanosomes into surface skin cells

autonomic sympathetic neurons , brain tissue & and transports monoamines (dopamine, norepinephrine, serotonin & histamine) from the cytoplasm into presynaptic storage vesicles Binds to the same site on VMAT1 & 2 as intracellular monoamines, producing a strong long-lasting inhibition of monoamine (e.g

has been shown to be effective