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Glutathione is typically used when you want a protein to sample the different disulfide bonds it could make to help it figure out the most energetically favorable disulfide bond (Lundstrm-Ljung & Holmgren, 1995)
When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations
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