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The GLP-1 receptor has also been located on mouse lung epithelial and endothelial cells, and on various immune cells such as human and mouse macrophages, eosinophils, neutrophils and lymphocytes [65, 70,71,72]
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A phase I clinical trial in patients with advanced colorectal cancer found that doses up to 3.6 g/day for four months were well tolerated, although the systemic bioavailability of oral curcumin was low (77)
144 Among them, P-gp/ABCB1, 145 MDR-associated proteins (MRPs/ABCCs), 146 and BCRP/ABCG2 147 are most extensively studied
Rev., 5(2), 191-211, 1989
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