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Regarding pharmacodynamics, TZP appears as a biased GLP-1R-GIPR co-agonist, because of its positive effects on cAMP generation over -arrestin recruitment, which is conversely stimulated by GLP-1R
The therapies were administered as single injections or infusions, and the regimens varied from study to study, ranging from a single dose to daily administration for a few days
The fact that they slow down digestion also helps keep blood sugar levels from spiking throughout the day
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