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A deficiency of B12 can lead to anemia and neurological abnormalities, but supplementation is a safe and cost-effective method of improving quality of life even when vitamin B12 levels are unknown
B12 deficiency can cause fatigue, mood changes, and difficulty concentrating
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10.1089/acm.2006.12.881 Summary Keywords vitamin B12, efficacy, bioavailability, therapeutic approaches, meta-analysis, cobalamin Citation Mazur M, Ndokaj A, Salerno C, Vallone J, Ardan R, Bietolini S, Carrouel F, Wilk A, Sarig R, Ottolenghi L and Bourgeois D (2025) Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis
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