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Child and maternal characteristics as covariates Child and maternal characteristics were collected through maternal interviews at the time of study enrollment within 2472 h of delivery and electronic medical records (EMR) abstraction

For instance, it may affect the metabolism of drugs that are substrates of the cytochrome P450 enzyme system, potentially altering their efficacy or toxicity

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After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation

Data availability Uncropped western blot images are provided in Supplementary Fig