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Lipkova, J
Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs
Upregulation of Antioxidant and Repair Genes: It increases the expression of genes responsible for DNA repair, antioxidant production (e.g., superoxide dismutase), and the synthesis of structural proteins like collagen and elastin
We acknowledge the assistance of the University of Texas Southwestern Tissue Management Shared Resource, a shared resource at the Simmons Comprehensive Cancer Center, which is supported in part by the National Cancer Institute under award number P30CA142543
Subcutaneous tissue has lower blood flow than muscle (0.03 mL/min/g versus 0.08 mL/min/g), so medications injected subQ absorb more slowly
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