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Putting them into a patch does not make them more effective, and in most cases the skin cant even absorb these ingredients properly

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The anti-inflammatory effects of KPV complement the regenerative effects of BPC-157

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However, once you combine these ingredients, the resulting treatment is no longer FDA-approved.16 We do appreciate that Winona uses approved ingredients, though, especially since some less-than-trustworthy manufacturers, as the Cleveland Clinic explains, may add untested hormones that are not FDA-approved and are unsafe to use.33 Insider Tip: Some of the treatments Winona uses are actually FDA-approved, such as the estrogen patches, estrogen tablets, and progesterone capsules