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The EMPA-REG OUTCOMES trial showed that empagliflozin, a SGLT-2i, markedly reduced the risk for HF hospitalization relative to the placebo ( HR = 0.65, 95% CI 0.500.85, P = 0.002) [96]
Front Pharmacol 29(12):646287
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Pregnant or nursing individuals without medical supervision
Researchers studying the broader axis often combine IGF-1 LR3 work with separate studies using GH secretagogues like CJC-1295/Ipamorelin or Tesamorelin to drive endogenous GH and IGF-1 production, then compare results
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