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rotundifolia has not been explored to date
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In Phase II clinical trials in adults with overweight or obesity, once-daily orforglipron led to 9-15% mean weight loss at 36 weeks, with a GI tolerability profile typical of the class
Theres some scientific rationale supporting this possibility, as it has been hypothesized that GLP1 agonists may decrease rewarding/reinforcing effects of alcohol and other drugs of abuse
