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This research was funded by the Fundamental Research Business Expenses of the Central Universities, grant number 2024GCZX002

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Because optic nerve tissue has limited ability to regenerate after ischemic injury, NAION is widely recognized as a potentially blinding eye disease that can have lifelong consequences for affected patients

Retatrutide has a six-day half-life, which means partial therapeutic levels persist even when a dose is missed, but consistency is important for steady adaptation during the starting period

Patients who clear their pigmentation and then return to unprotected sun exposure without this kind of maintenance will typically see pigmentation return within 3 to 6 months, so the sunscreen recommendation is treated as part of the prescription, not an afterthought