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If you need an early refill because your medication was compromised, your pharmacist can sometimes process it as a "lost or damaged medication" override
The chemical modification of the molecule is aimed at reducing its rate of degradation (so it acts longer after administration)
Bannuru RR, Osani MC, Vaysbrot EE, Arden NK, Bennell K, Bierma-Zeinstra SMA, Kraus VB, Lohmander LS, Abbott JH, Bhandari M, Blanco FJ, Espinosa R, Haugen IK, Lin J, Mandl LA, Moilanen E, Nakamura N, Snyder-Mackler L, Trojian T, Underwood M, Mcalindon TE