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Unlike mammalian extracellular vesicles, which are enriched in cholesterol-containing lipid rafts, PDEVs lack cholesterol-rich domains and instead incorporate plant-specific lipids and cell wallderived polysaccharides, such as glycosylinositolphosphoceramides (GIPCs) [51, 52]

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Typical daily range: 510 mg once daily (gradual titration)

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