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In the general population, IR and MetS induce hyperlipidemia and hyperglycemia

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However, the dual role of ROS as signaling molecules and toxins requires a delicate approach, as indiscriminate inhibition of ROS may disrupt physiological signaling [14, 539, 558]

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2.4 Sample size calculation The study was designed to include 16 eyes (8 in each group), providing a 95% statistical power to detect a significant difference between the hyaluronic acid + glutathione group and the hyaluronic acid-only group, assuming a 20% dispersion index and a two-sided = 0.05 ( 2.5 Study procedures All tests and data collection were performed by a cornea specialist