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It is about support

It does not give a precise percentage for fatigue, because the drug's most common adverse reactions, reported in at least 5% of patients, are nausea, vomiting, diarrhea, abdominal pain and constipation

Weekly dosing also means the interval is about one half-life, so drug accumulates and steady state takes four to six weeks

Herbal teas offer a caffeine-free alternative that many patients tolerate well

Dr Hendershot acknowledges support from the Department of Psychiatry and Bowles Center for Alcohol Studies, University of North Carolina Chapel Hill School of Medicine.