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Naunyn-Schmiedeberg's Archives of Pharmacology

Since the cellular synthesis of glutathione is ATP-dependent, decreased ETC activity also undermines glutathione synthesis, further exacerbating oxidative stress in a vicious cycle [8]

FEBS Lett

Various studies have attempted to quantify how much fat versus muscle mass is being lost when using GLP-1 agonists and the results vary anywhere from 20 to 50% of total weight loss as lean body mass (3) (muscle mass)