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What the topline cannot show is how many patients are still on it at week 80 in a real clinic.

Optimization strategies for both treatments involve personalized dosing, regular GH level monitoring, and lifestyle modifications to maximize results while minimizing side effects

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Sasaki et al

However, most plans exclude coverage for weight loss medications or impose strict eligibility criteria like BMI above 30 with comorbidities or BMI above 27 with diabetes