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Louis Aronne has noted, while these drugs demonstrate remarkable efficacy, there remains a need for ongoing advancements in weight-loss drug development to better meet the needs of all patients

Initially, these medications were developed for the treatment of type 2 diabetes mellitus, but GLP-1 RA drugs have demonstrated remarkable outcomes in clinical settings

Ingredients: Plant sterols, inulin, phenolic glycosides, flavonoids, phylloquinone (vitamin K1), rosae extract, pruni cum inulin extract, 24-methylcholesta-5,22-dien-3 beta-ol, stigmast-5-en-3-ol, 24alpha-methylcholesterol, dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, capsule shell (gelatin)

While GLP-1 receptors are present in the kidneys and may have mild natriuretic effects, they do not typically cause clinically significant polyuria (excessive urination) in the way that diuretic medications do

Neurosci Biobehav Rev 114:134