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Diabetes, Obesity and Metabolism, 22(10), 18861891
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Furthermore, in a phase 2 clinical trial addressing a patient group with type 2 diabetes and overweight/obesity, after 32 weeks of treatment, the cagrisema 2.4 mg group exhibited a more significant average weight loss compared to the cagrilintide 2.4 mg group or the group using semaglutide 2.4 mg alone, with reductions of 15.6%, 8.1%, and 5.1%, respectively
Whilst generally causing fewer gastrointestinal side effects than GLP-1 receptor agonists, they provide more modest glycaemic benefits and lack the weight loss and cardiovascular benefits associated with Ozempic
Semaglutide was also associated with a modest but statistically significant greater reduction in HbA1c (adjusted = 0.29%-point
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