Elevated serum B12 levels (hypercobalaminaemia) often serve as a biomarker for serious underlying conditions rather than being directly harmful themselves
Treatment when there is a clear pattern of neurological symptoms
Both these methylation reactions are vital for growth and cell reproduction.[9][10] Methionine, a sulfur-containing, essential amino acid, is a precursor of S-adenosylmethionine, a cofactor for one-carbon metabolism and the final methyl donor for the methylation of DNA, RNA, proteins, and phospholipids.[11] The methionine synthase plays a paramount role in the synthesis of nitrogenous bases (purines and pyrimidines) involved in the formation of DNA
B12 injections can reverse or prevent a deficiency, help maintain red blood cells, and increase energy levels, brain function, mood, metabolism, and weight loss by boosting the production of red blood cells
Processing of cholesterol and protein gives propionyl-CoA that is converted to methylmalonyl-CoA, which is used by MUT enzyme to make succinyl-CoA