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380056) from 6 to 18 weeks of age, and co-housed with counterparts on the same diet, were purchased from The Jackson Laboratory (Bar Harbor, ME, USA)
Early studies in obese individuals showed some reductions in body fat mass, but findings are not consistent across trials: In one clinical trial, AOD9604 did not demonstrate statistically significant weight loss compared to placebo, suggesting its fat-burning effects may be modest without lifestyle intervention (summary of trials)
Some wellness programs include B12 shots for weight loss alongside balanced nutrition and physical activity
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