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Description

These side effects are usually mild and often improve over time

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Niacinamide: At higher doses, temporary flushing or mild gastrointestinal symptoms may occur

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New Scientist

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Moreover, the success of incretin-based therapies has recalibrated tolerance for certain classes of adverse effects when balanced against substantial clinical benefit

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A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

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