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FDA-approved GLP-1 receptor agonists come in short-acting and long-acting forms
In the 1960s and 70s, scientists were puzzled by the observation that oral glucose caused a much greater insulin response than intravenous glucose
For tissue repair, cartilage healing, or chronic arthritis, meaningful change usually shows up after 4 to 6 weeks of consistent treatment
Subsequent increases of 2.5 mg occur every four weeks as tolerated, up to a maximum of 15 mg per week
The GLP-1 agonists have excellent patient outcomes
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