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BI 3032950 is a TREM-1 antagonist currently in Phase 2 development for immunology applications, specifically being investigated for moderate to severe UC in trial (NCT06636656)
Some individuals demonstrate robust GH elevation with either compound
Native GLP-1 and AMG 133 both induce complete agonism of human GLP-1R, with respective EC 50 values of 4.1 and 24.4 pM (Extended Data Fig
This article is for informational purposes only and reflects a summary of current research that is referenced at the end of this article
doi:10.1056/NEJMoa2307563 Kosiborod MN, et al
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