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The evidence tier that is fully published and verifiable is Phase 2
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469,470 A recent study demonstrated that subcutaneous injection of a CPP-DG9 and PMO conjugate improved muscle strength and innervation in mice with severe SMA, significantly extending their median survival with no apparent side effects
There are some lab markers that may be helpful in addressing MCAS: DAO enzymes this is an enzyme that breaks down histamine, so checking for deficiencies can be helpful
Seizures: There have been very rare reports of seizures in individuals with or without a history of seizure disorders
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