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While these findings highlight multiple possible mechanisms, the pathways remain under active exploration

Studies indicate that without intervention, up to 25% of weight lost during aggressive dieting comes from lean muscle mass rather than fat

Timing of administration relative to surgical procedures, optimal dosing in perioperative settings, and integration with standard post-operative care protocols require clinical investigation before establishing evidence-based perioperative protocols

Role of G6PD-deficiency-mediated RBC hemolysis in ASCVD Any discussion of the potential impact of G6PD-d on ASCVD would be incomplete without considering how the predominant hemolytic phenotype may contribute to worsened disease