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10 Advice on GLP-1 RA use is expected to be updated as part of the latest review of the NICE NG28 guideline on type 2 diabetes management, which has an expected publication date of December 2024

Duseja 4 , Pankaj Gupta 3 , Naveen Kalra 3 , Ekta Gupta 5 , Gagandeep Singh Grover 6 , Anchal Sandhu 3 , Harish Bhujade 3 , Sreedhara B Chaluvashetty 3 , Manoj Kumar 7 , Sunil Taneja 4 , Sahaj Rathi 3 , Nipun Verma 4 , Suvradeep Mitra 3 , Divya Khosla 3 , Jasvinder Nain 3 , Vishesh Kumar 3 , Prerna Sharma 3 and Surender Singh 3 , (1)Postgraduate Institute of Medical Education & Research, Chandigarh, India, (2)Sanjay Gandhi Postgraduate Institute of Medical Sciences, (3)Post Graduate Institute of Medical Education and Research, (4)Post Graduate Institute of Medical Education and Research, Chandigarh, India, (5)Institute of Liver and Biliary Sciences, (6)Punjab Government, (7)Institute of Microbial Technology (CSIR-IMTECH) Background: The Punjab HCV Model, a decentralized multicentric public health cohort, has resulted in cure rates of 91.6% using free-of-charge generic direct-acting antiviral agents (DAAs) in patients with chronic hepatitis C (CHC) infection

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Of note, we found that Ex-4 binding to GLP-1R leads to increased cAMP levels, an elevated ISR, and reduced glucagon secretion, all consistent with previous findings

Tiered vital-sign capture is uncommon outside hospital intake YOUR APPROVAL EXPIRES IN 14:54 fake-urgency timer Clinical Safety Screens Performed Suicidal thoughts and/or prior attempt named directly Current or prior eating disorder named Pancreatitis personal history (current or past) Pregnancy / breastfeeding / postpartum 6 months End-stage kidney + liver disease separately named T1D, T2D-on-insulin, T2D-not-on-insulin distinguished Diabetic retinopathy + warfarin use Opiate use last 3 months including street drugs Bariatric / abdominal / pelvic surgery BP tiered to AHA staging + HR tiered HTN, sleep apnea, high cholesterol, acid reflux Food allergies 7-option separate from medication allergies Most cash-pay GLP-1 funnels either skip blood pressure entirely or ask a single threshold yes/no (Is your BP above 140/90?)