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What has been promising about Mounjaro is that similar to GLP-1 agonists, it is a diabetes medication that can lead to weight loss
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For the SURPASS-CVOT emulation (tirzepatide vs dulaglutide), the hazard ratio for MACE was 0.83 (95% CI, 0.691.01) compared with 0.92 (95% CI, 0.831.01) in the trial, satisfying all concordance criteria
For example, monoclonal antibodies targeting this pathway are being studied in cancer treatments, with potential for future autoimmune therapies (6)
M-II does not display any inhibitory activity toward DPP-4 or other DPP-related enzymes
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