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After discontinuation, weight recurrence followed predictable patterns: 4.5% regain at 3 months 5.9% at 6 months 7.5% after one year Those without diabetes tended to regain more weight, while diabetes patients showed slightly better maintenance, possibly due to structured follow-up or concurrent metabolic care
Upon activation by GLP-1RAs, GLP-1R initiates diverse intracellular cascades, such as the cyclic adenosine monophosphate (cAMP) / protein kinase A (PKA) pathway and phosphatidylinositol 3-kinase (PI3K) / protein kinase B (Akt) signaling pathway [1, 9]
W.MillerJ.et al (2013)
Most people are chronically under-hydrated
In an elderly patient, should I prescribe Jardiance (empagliflozin) or a GLP-1 (glucagon-like peptide-1) receptor agonist for glycemic control?
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