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Prasad K, Mishra M

Specifically, through the FSP1-CoQ10-NAD (P)H pathway, it adeptly counters CoQ10-mediated ferroptosis, operating in a manner that runs parallel to the well-established GPX4 pathway [53]

Furthermore, heme can drive TNF-- and ROS-mediated necroptosis [225], heme oxygenase 1-dependent ferroptosis [226], and NLRP3 inflammasome-associated pyroptosis [227], which are highly proinflammatory RCDs

Differences in antioxidant responses to drought in C3 and C4 plants are few, but they may be essential in understanding the metabolic antioxidant patterns of these two plant groups