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Maintaining hydration supports kidney function, skin health, and even helps to curb false hunger signals

[1] [2] Patients should not advance to higher doses prematurely, even if glycemic or weight loss goals have not yet been achieved

While promising results have been observed in animal studies and anecdotal reports, comprehensive clinical trials are necessary to establish its safety and efficacy

Moreover, the comparison between DPP-4 inhibitors and placebo demonstrated no difference in their risk for MACE (RR = 0.99, 95% CI 0.931.06)

Discontinuation rates due to gastrointestinal adverse effects ranged from 4% to 7% across clinical trials