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Clin Chem (2003) 49(2):295302.10.1373/49.2.295 92 ZhuYZhuR-XHeZ-YLiuXLiuH-N

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in fact, elevated GPx levels have been reported in CF sputum ( 2 O 2 levels, which contribute to the overproduction of pro-inflammatory cytokines like IL-6 and IL-8, directly linking defective antioxidant response to CFs characteristic chronic inflammation ( 2 O 2 processing and significantly reduced inflammatory cytokine production in CF cells ( 5.1.7.4 Oxidative stress and inflammatory pathways The interplay between oxidative stress and inflammation is a defining characteristic of CF lung disease, creating a vicious cycle of damage

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