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Researchers should confirm that the batch or lot number shown on the supplied vial matches the batch number stated on the accompanying Certificate of Analysis

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Before administering parenteral vitamin therapies, clinics must obtain informed consent, disclosing potential benefits, risks, contraindications, and aftercare requirements

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Those most at risk include vegans and vegetarians, people with digestive conditions such as Crohn's disease, coeliac disease or IBS, those taking long-term metformin or proton pump inhibitors, older adults whose ability to absorb B12 through the gut declines naturally with age, those with pernicious anaemia, and anyone with a history of chronic alcohol use