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Side Effects Both medications come with potential side effects: Semaglutide: Nausea and vomiting Diarrhea or constipation Low blood sugar (hypoglycemia) Topiramate: Dizziness and fatigue Numbness or tingling in the extremities Mood changes or difficulty concentrating While side effects may vary from person to person, they often diminish over time as the body adjusts to the medication

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Her lymphedema was well controlled but required daily compression with a negligible limb volume difference of 1.7%