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Patients should provide a complete medication list, including all prescription medications, over-the-counter drugs, supplements, and herbal products

Because pigmentation reflects downstream cellular changes rather than an immediate on/off response, observed effects are typically gradual and depend on individual biology, baseline skin type, UV exposure, and melanocyte activity

This test is often scheduled in the morning when testosterone naturally peaks, although the differences become less significant throughout the day for older men

Curr Atheroscler Rep (2022) 24:86784