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Hydroxocobalamin may also be given intravenously in certain scenarios (for example, 5 g IV for acute cyanide poisoning antidote therapy), but such high-dose use is in emergency settings and distinct from routine deficiency treatment
Claimed outcome Human weight loss Evidence level Not established What research currently shows No controlled human trial has shown that 5-Amino-1MQ causes weight loss
Doctors in the UK are expected to practice in line with evidence-based guidelines
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Most clinicians recommend B12 injections every 1 to 4 weeks for deficiency treatment and once a month for maintenance after deficiency is corrected
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