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Both berberine and oral semaglutide reduce blood glucose through overlapping but mechanistically distinct pathways, so their glucose-lowering effects add together rather than cancel
An oral dissolving tablet gives us an option to offer something between a GLP-1 and cold turkey stopping, which leads to weight regain
Ozempic is generally a lot more expensive than metformin
The anti-inflammatory effect does not rely on melanocortin receptors but works specifically through PepT1, helping KPV enter inflamed cells
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