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Key Features: Peptide is digested using enzymes (e.g., trypsin) Produces smaller, more manageable fragments Easier data interpretation and sequence reconstruction Best Use Case: Routine analysis, impurity profiling, and confirmation of known sequences

Efficacy and safety of intranasal peptide YY336 for weight reduction in obese adults

Few subjects ( N = 29) developed anti-semaglutide antibodies, and the presence of antibodies did not appear to be related to a difference in exposure, as exposures in subjects with antibodies were similar to those observed in subjects without antibodies (data on file)

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