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4- triazol-3-one-d4
Synthetic MUC-1 (di-Tn)-Cys glycopeptide
with the sugar hydroxyl groups protected as acetate esters
C24H40N2O11 / 532
/ α-L-Rha-Ethyl-Amine / α-Rha-Et-NH2
PE131010: β-GalNAc-PEG3-Alkyne label-new 4- triazol-3-one-d4C17H29NO9 391. 41 A D N acetylgalactosamine (GalNAc) ligand equipped with a terminal alkyne through a hydrophilic PEG3 spacer. The alkyne couples to azide functionalized partners via copper catalyzed azide alkyne cycloaddition (CuAAC), forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR), which is highly expressed on
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